/* ============================================================
   PEPTIDE ATLAS — Design System
   Direction : laboratoire scientifique sombre, verre et précision.
   ============================================================ */

:root {
  /* Couleurs primitives */
  --color-bg: #0a0e14;
  --color-bg-elevated: #10151f;
  --color-bg-card: #131926;
  --color-border: #1f2733;
  --color-border-strong: #2c3648;

  --color-text: #e7ecf4;
  --color-text-muted: #8b96a8;
  --color-text-faint: #5c6577;

  --color-accent: #4fd6c4;       /* cyan laboratoire */
  --color-accent-dim: #2a7f75;
  --color-accent-glow: rgba(79, 214, 196, 0.18);

  /* Couleurs sémantiques de preuve / risque */
  --color-evidence-high: #4fd6c4;
  --color-evidence-moderate: #6fb3e8;
  --color-evidence-limited: #d9b25b;
  --color-evidence-preclinical: #b98cd6;
  --color-evidence-hypothesis: #8b96a8;
  --color-evidence-insufficient: #5c6577;

  --color-risk-low: #3ba876;
  --color-risk-moderate: #d9b25b;
  --color-risk-high: #e0625f;
  --color-risk-unknown: #5c6577;

  --radius-sm: 6px;
  --radius-md: 10px;
  --radius-lg: 18px;

  --shadow-card: 0 1px 0 rgba(255,255,255,0.03) inset, 0 8px 24px rgba(0,0,0,0.35);
  --font-display: 'Fraunces', Georgia, serif;
  --font-body: 'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', sans-serif;
  --font-mono: 'JetBrains Mono', 'Courier New', monospace;

  --max-width: 1280px;
}

@media (prefers-color-scheme: light) {
  :root:not([data-theme="dark"]) {
    --color-bg: #f7f8fa;
    --color-bg-elevated: #ffffff;
    --color-bg-card: #ffffff;
    --color-border: #e2e5eb;
    --color-border-strong: #cbd1dc;
    --color-text: #131926;
    --color-text-muted: #566073;
    --color-text-faint: #8b96a8;
  }
}

* { box-sizing: border-box; }

html { scroll-behavior: smooth; }

@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
  *, *::before, *::after {
    animation-duration: 0.001ms !important;
    animation-iteration-count: 1 !important;
    transition-duration: 0.001ms !important;
  }
}

body {
  margin: 0;
  background: var(--color-bg);
  color: var(--color-text);
  font-family: var(--font-body);
  font-size: 16px;
  line-height: 1.6;
  -webkit-font-smoothing: antialiased;
}

a { color: var(--color-accent); text-decoration: none; }
a:hover { text-decoration: underline; }

.container {
  max-width: var(--max-width);
  margin: 0 auto;
  padding: 0 24px;
}

/* ---------- En-tête ---------- */
.site-header {
  position: sticky;
  top: 0;
  z-index: 50;
  background: rgba(10, 14, 20, 0.85);
  backdrop-filter: blur(10px);
  border-bottom: 1px solid var(--color-border);
}
.header-inner {
  display: flex;
  align-items: center;
  justify-content: space-between;
  height: 68px;
  gap: 24px;
}
.brand {
  display: flex;
  align-items: center;
  gap: 10px;
  font-family: var(--font-display);
  font-size: 1.25rem;
  color: var(--color-text);
  font-weight: 600;
  letter-spacing: 0.01em;
}
.brand-mark {
  width: 28px; height: 28px;
  border-radius: 50%;
  background: radial-gradient(circle at 30% 30%, var(--color-accent), var(--color-accent-dim));
  box-shadow: 0 0 18px var(--color-accent-glow);
  flex-shrink: 0;
}
.main-nav { display: flex; gap: 4px; align-items: center; }
.main-nav a {
  color: var(--color-text-muted);
  font-size: 0.92rem;
  padding: 8px 14px;
  border-radius: var(--radius-sm);
  text-decoration: none;
  transition: color 0.15s, background 0.15s;
}
.main-nav a:hover, .main-nav a.active {
  color: var(--color-text);
  background: var(--color-bg-elevated);
}

/* ---------- Hero ---------- */
.hero {
  position: relative;
  padding: 96px 0 72px;
  overflow: hidden;
  border-bottom: 1px solid var(--color-border);
  background:
    radial-gradient(60% 50% at 80% 0%, var(--color-accent-glow), transparent 70%),
    radial-gradient(40% 40% at 10% 100%, rgba(139, 140, 214, 0.08), transparent 70%);
}
.hero-grid {
  position: absolute; inset: 0;
  background-image:
    linear-gradient(var(--color-border) 1px, transparent 1px),
    linear-gradient(90deg, var(--color-border) 1px, transparent 1px);
  background-size: 64px 64px;
  opacity: 0.25;
  mask-image: radial-gradient(circle at 70% 20%, black, transparent 70%);
}
.hero-content { position: relative; max-width: 720px; }

.hero-molecule {
  position: absolute;
  top: 50%; right: -4%;
  transform: translateY(-50%);
  width: min(46vw, 560px);
  height: auto;
  opacity: 0.9;
  pointer-events: none;
}
.hero-molecule .mol-bond { stroke: var(--color-border-strong); stroke-width: 1.2; }
.hero-molecule .mol-atom-1 { fill: var(--color-accent); }
.hero-molecule .mol-atom-2 { fill: #8b8cd6; }
.hero-molecule .mol-node { transform-origin: center; animation: mol-float 7s ease-in-out infinite; }
.hero-molecule .mol-b, .hero-molecule .mol-e { animation-delay: -1.4s; animation-duration: 8.5s; }
.hero-molecule .mol-c, .hero-molecule .mol-f { animation-delay: -3.1s; animation-duration: 6.2s; }
.hero-molecule .mol-d, .hero-molecule .mol-g { animation-delay: -4.8s; animation-duration: 9s; }
@keyframes mol-float {
  0%, 100% { transform: translate(0, 0); }
  50% { transform: translate(0, -10px); }
}
@media (prefers-reduced-motion: reduce) {
  .hero-molecule .mol-node { animation: none; }
}
@media (max-width: 900px) {
  .hero-molecule { opacity: 0.35; width: 70vw; }
}
.eyebrow {
  display: inline-flex; align-items: center; gap: 8px;
  font-size: 0.78rem; text-transform: uppercase; letter-spacing: 0.12em;
  color: var(--color-accent);
  margin-bottom: 20px;
  font-weight: 600;
}
.hero h1 {
  font-family: var(--font-display);
  font-size: clamp(2.2rem, 5vw, 3.4rem);
  line-height: 1.1;
  margin: 0 0 20px;
  font-weight: 500;
}
.hero p.lead {
  font-size: 1.15rem;
  color: var(--color-text-muted);
  max-width: 56ch;
  margin: 0 0 32px;
}
.hero-actions { display: flex; gap: 12px; flex-wrap: wrap; }

.search-box {
  margin-top: 40px;
  max-width: 560px;
  position: relative;
}
.search-box input {
  width: 100%;
  padding: 16px 20px 16px 48px;
  border-radius: var(--radius-lg);
  border: 1px solid var(--color-border-strong);
  background: var(--color-bg-elevated);
  color: var(--color-text);
  font-size: 1rem;
}
.search-box input:focus {
  outline: 2px solid var(--color-accent);
  outline-offset: 2px;
}
.search-box::before {
  content: "";
  position: absolute; left: 18px; top: 50%; transform: translateY(-50%);
  width: 18px; height: 18px;
  border: 2px solid var(--color-text-faint);
  border-radius: 50%;
}

/* ---------- Boutons ---------- */
.btn {
  display: inline-flex; align-items: center; gap: 8px;
  padding: 12px 22px;
  border-radius: var(--radius-md);
  font-size: 0.95rem;
  font-weight: 600;
  cursor: pointer;
  border: 1px solid transparent;
  text-decoration: none;
  transition: transform 0.12s, box-shadow 0.12s, background 0.15s;
}
.btn:hover { text-decoration: none; }
.btn-primary {
  background: var(--color-accent);
  color: #06110f;
}
.btn-primary:hover { box-shadow: 0 0 0 4px var(--color-accent-glow); }
.btn-secondary {
  background: transparent;
  color: var(--color-text);
  border-color: var(--color-border-strong);
}
.btn-secondary:hover { border-color: var(--color-accent); }
.btn-sm { padding: 8px 14px; font-size: 0.85rem; }
.btn-danger { background: var(--color-risk-high); color: #fff; }

/* ---------- Sections génériques ---------- */
.section { padding: 64px 0; }
.section-header {
  display: flex; align-items: baseline; justify-content: space-between;
  margin-bottom: 32px; flex-wrap: wrap; gap: 12px;
}
.section-header h2 {
  font-family: var(--font-display);
  font-size: 1.8rem; font-weight: 500; margin: 0;
}
.section-header p { color: var(--color-text-muted); margin: 4px 0 0; }

/* ---------- Grille de cartes produits ---------- */
.product-grid {
  display: grid;
  grid-template-columns: repeat(auto-fill, minmax(280px, 1fr));
  gap: 20px;
}
.product-card {
  background: var(--color-bg-card);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-lg);
  padding: 22px;
  box-shadow: var(--shadow-card);
  transition: border-color 0.15s, transform 0.15s;
  display: flex; flex-direction: column; gap: 12px;
}
.product-card:hover { border-color: var(--color-border-strong); transform: translateY(-2px); }
.product-card .vial {
  width: 100%; height: 130px;
  border-radius: var(--radius-md);
  background: radial-gradient(circle at 50% 30%, rgba(79,214,196,0.08), transparent 70%);
  display: flex; align-items: center; justify-content: center;
  border: 1px solid var(--color-border);
  padding: 10px 0;
}
.vial-svg { height: 100%; width: auto; max-width: 100px; }
.product-card h3 { margin: 0; font-size: 1.05rem; font-family: var(--font-display); font-weight: 600; }
.product-card .aliases { color: var(--color-text-faint); font-size: 0.82rem; }
.product-card .summary { color: var(--color-text-muted); font-size: 0.88rem; flex-grow: 1; }
.tags-row { display: flex; gap: 6px; flex-wrap: wrap; }

.badge {
  display: inline-flex; align-items: center; gap: 6px;
  padding: 3px 9px; border-radius: var(--radius-sm);
  font-size: 0.7rem; font-weight: 600;
  letter-spacing: 0.02em;
  border: 1px solid var(--color-border-strong);
  white-space: nowrap;
}
.badge-dot { width: 5px; height: 5px; border-radius: 50%; flex-shrink: 0; }

/* ---------- Filtres catalogue ---------- */
.catalog-layout { display: grid; grid-template-columns: 260px 1fr; gap: 32px; align-items: start; }
.filters-panel {
  background: var(--color-bg-card);
  border: 1px solid var(--color-border);
  border-radius: var(--radius-lg);
  padding: 20px;
  position: sticky; top: 88px;
}
.filters-panel h4 { font-size: 0.8rem; text-transform: uppercase; letter-spacing: 0.08em; color: var(--color-text-faint); margin: 18px 0 10px; }
.filters-panel h4:first-child { margin-top: 0; }
.filter-option { display: flex; align-items: center; gap: 8px; padding: 6px 0; font-size: 0.9rem; }
.filter-option input { accent-color: var(--color-accent); }
.results-count { color: var(--color-text-muted); font-size: 0.9rem; margin-bottom: 16px; }

@media (max-width: 900px) {
  .catalog-layout { grid-template-columns: 1fr; }
  .filters-panel { position: static; }
}

/* ---------- Fiche produit ---------- */
.product-hero { padding: 56px 0 40px; border-bottom: 1px solid var(--color-border); }
.product-hero-grid { display: grid; grid-template-columns: 280px 1fr; gap: 40px; }
.product-hero .vial-large { height: 320px; display: flex; align-items: center; justify-content: center; }
.product-hero .vial-large .vial-svg { height: 90%; max-width: 160px; }
.product-title-row { display: flex; align-items: baseline; gap: 16px; flex-wrap: wrap; margin-bottom: 8px; }
.product-title-row h1 { font-family: var(--font-display); font-size: 2.4rem; margin: 0; font-weight: 500; }
.disclaimer-box {
  background: rgba(217, 178, 91, 0.08);
  border: 1px solid rgba(217, 178, 91, 0.35);
  border-radius: var(--radius-md);
  padding: 14px 18px;
  font-size: 0.85rem;
  color: #d9b25b;
  margin: 16px 0;
}
.disclaimer-box.danger {
  background: rgba(224, 98, 95, 0.08);
  border-color: rgba(224, 98, 95, 0.4);
  color: #e0625f;
}

.tabs { display: flex; gap: 4px; border-bottom: 1px solid var(--color-border); margin: 40px 0 32px; overflow-x: auto; }
.tab-btn {
  padding: 12px 18px; background: none; border: none; cursor: pointer;
  color: var(--color-text-muted); font-size: 0.92rem; font-weight: 600;
  border-bottom: 2px solid transparent; white-space: nowrap;
}
.tab-btn.active { color: var(--color-text); border-bottom-color: var(--color-accent); }
.tab-panel { display: none; }
.tab-panel.active { display: block; }

.reading-level-switch { display: inline-flex; background: var(--color-bg-card); border: 1px solid var(--color-border); border-radius: 999px; padding: 4px; margin-bottom: 24px; }
.reading-level-switch button {
  border: none; background: none; padding: 8px 16px; border-radius: 999px;
  color: var(--color-text-muted); cursor: pointer; font-size: 0.85rem; font-weight: 600;
}
.reading-level-switch button.active { background: var(--color-accent); color: #06110f; }
.reading-content { display: none; }
.reading-content.active { display: block; }

.data-table { width: 100%; border-collapse: collapse; font-size: 0.9rem; }
.data-table th, .data-table td { text-align: left; padding: 12px 14px; border-bottom: 1px solid var(--color-border); }
.data-table th { color: var(--color-text-faint); font-weight: 600; text-transform: uppercase; font-size: 0.72rem; letter-spacing: 0.06em; }

.effect-list { list-style: none; padding: 0; margin: 0; display: grid; gap: 8px; }
.effect-list li { display: flex; align-items: center; gap: 10px; padding: 10px 14px; background: var(--color-bg-card); border: 1px solid var(--color-border); border-radius: var(--radius-sm); font-size: 0.9rem; }

.source-card { background: var(--color-bg-card); border: 1px solid var(--color-border); border-radius: var(--radius-md); padding: 16px 18px; margin-bottom: 10px; }
.source-card .meta { color: var(--color-text-faint); font-size: 0.8rem; margin-top: 4px; }

.card-panel { background: var(--color-bg-card); border: 1px solid var(--color-border); border-radius: var(--radius-lg); padding: 24px; box-shadow: var(--shadow-card); }

/* ---------- Calculateur ---------- */
.calc-layout { display: grid; grid-template-columns: 1fr 1fr; gap: 32px; }
@media (max-width: 800px) { .calc-layout { grid-template-columns: 1fr; } }
.form-group { margin-bottom: 18px; }
.form-group label { display: block; font-size: 0.85rem; color: var(--color-text-muted); margin-bottom: 6px; font-weight: 600; }
.form-group input, .form-group select {
  width: 100%; padding: 11px 14px; border-radius: var(--radius-sm);
  border: 1px solid var(--color-border-strong); background: var(--color-bg-elevated); color: var(--color-text);
  font-size: 0.95rem;
}
.form-row { display: grid; grid-template-columns: 1fr 1fr; gap: 14px; }
.result-row { display: flex; justify-content: space-between; padding: 14px 0; border-bottom: 1px solid var(--color-border); }
.result-row .label { color: var(--color-text-muted); }
.result-row .value { font-family: var(--font-mono); font-weight: 600; font-size: 1.05rem; }
.result-highlight { background: var(--color-accent-glow); border: 1px solid var(--color-accent); border-radius: var(--radius-md); padding: 20px; margin-top: 16px; }

/* ---------- Formulaires admin / login ---------- */
.auth-shell { min-height: 100vh; display: flex; align-items: center; justify-content: center; background: var(--color-bg); }
.auth-card { width: 100%; max-width: 400px; background: var(--color-bg-card); border: 1px solid var(--color-border); border-radius: var(--radius-lg); padding: 40px; }
.field-error { color: var(--color-risk-high); font-size: 0.85rem; margin-top: 6px; }
.alert { padding: 14px 16px; border-radius: var(--radius-sm); font-size: 0.9rem; margin-bottom: 18px; }
.alert-error { background: rgba(224,98,95,0.1); border: 1px solid rgba(224,98,95,0.4); color: #e0625f; }
.alert-success { background: rgba(59,168,118,0.1); border: 1px solid rgba(59,168,118,0.4); color: #3ba876; }

/* ---------- Admin layout ---------- */
.admin-shell { display: grid; grid-template-columns: 240px 1fr; min-height: 100vh; }
.admin-sidebar { background: var(--color-bg-elevated); border-right: 1px solid var(--color-border); padding: 20px 14px; }
.admin-sidebar nav a {
  display: block; padding: 10px 14px; border-radius: var(--radius-sm); color: var(--color-text-muted);
  font-size: 0.9rem; margin-bottom: 2px;
}
.admin-sidebar nav a:hover, .admin-sidebar nav a.active { background: var(--color-bg-card); color: var(--color-text); text-decoration: none; }
.admin-main { padding: 32px 40px; }
.admin-topbar { display: flex; justify-content: space-between; align-items: center; margin-bottom: 28px; }
.stat-grid { display: grid; grid-template-columns: repeat(auto-fit, minmax(180px, 1fr)); gap: 16px; margin-bottom: 32px; }
.stat-card { background: var(--color-bg-card); border: 1px solid var(--color-border); border-radius: var(--radius-md); padding: 18px 20px; }
.stat-card .num { font-family: var(--font-display); font-size: 1.9rem; }
.stat-card .lbl { color: var(--color-text-muted); font-size: 0.82rem; }
.admin-table { width: 100%; border-collapse: collapse; }
.admin-table th, .admin-table td { text-align: left; padding: 12px 14px; border-bottom: 1px solid var(--color-border); font-size: 0.9rem; }
.admin-table th { color: var(--color-text-faint); text-transform: uppercase; font-size: 0.72rem; letter-spacing: 0.05em; }
.admin-table tr:hover td { background: var(--color-bg-elevated); }

@media (max-width: 860px) {
  .admin-shell { grid-template-columns: 1fr; }
  .admin-sidebar { display: flex; overflow-x: auto; border-right: none; border-bottom: 1px solid var(--color-border); }
  .product-hero-grid { grid-template-columns: 1fr; }
}

/* ---------- Pied de page ---------- */
.site-footer { border-top: 1px solid var(--color-border); padding: 48px 0; margin-top: 80px; color: var(--color-text-muted); font-size: 0.88rem; }
.footer-grid { display: grid; grid-template-columns: 2fr 1fr 1fr 1fr; gap: 32px; }
.footer-grid h5 { color: var(--color-text); font-size: 0.85rem; margin: 0 0 12px; }
.footer-grid a { display: block; color: var(--color-text-muted); padding: 4px 0; font-size: 0.85rem; }
.footer-bottom { margin-top: 32px; padding-top: 24px; border-top: 1px solid var(--color-border); font-size: 0.8rem; color: var(--color-text-faint); }
@media (max-width: 700px) { .footer-grid { grid-template-columns: 1fr 1fr; } }

.empty-state { text-align: center; padding: 60px 20px; color: var(--color-text-muted); }